Aliases
Cell division inhibitor SulA, sulA, sfiA, b0958, JW0941
Antibody Type
Polyclonal Antibody
Species
Escherichia coli
Uniprot ID
P0AFZ5
Immunogen
Recombinant Escherichia coli Cell division inhibitor SulA protein (1-169AA)
Raised In
Rabbit
Species Reactivity
Escherichia coli
Tested Applications
ELISA;Not yet tested in other applications.
Background / Function
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. The effect of overexpression of SulA is neutralized by antitoxin CbeA (yeeU) (PubMed:22515815).
Isotype
IgG
Conjugate
Unconjugated
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
>95%,Protein G purified
