Description
Aliases
EKC/KEOPS complex subunit TPRKB, PRPK-binding protein, TP53RK-binding protein, TPRKB, CGI-121, My019
Antibody Type
Polyclonal Antibody
Species
Human
Uniprot ID
Q9Y3C4
Immunogen
Recombinant human EKC/KEOPS complex subunit TPRKB protein (1-175AA)
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA, WB, IHC;Not yet tested in other applications.
Background / Function
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TPRKB acts as an allosteric effector that regulates the t(6)A activity of the complex. TPRKB is not required for tRNA modification.
Isotype
IgG
Conjugate
Unconjugated
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
>95%,Protein G purified
Additional information
| Size | 50μg, 100μg |
|---|
