Aliases
Translocating chain-associated membrane protein 2, TRAM2, KIAA0057
Antibody Type
Polyclonal Antibody
Species
Human
Uniprot ID
Q15035
Immunogen
Recombinant human Translocating chain-associated membrane protein 2 protein (316-370AA)
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA, IHC, IF;Recommended dilution:IHC:1:20-1:200, IF:1:50-1:200
Background / Function
Necessary for collagen type I synthesis. May couple the activity of the ER Ca(2+) pump SERCA2B with the activity of the translocon. This coupling may increase the local Ca(2+) concentration at the site of collagen synthesis, and a high Ca(2+) concentration may be necessary for the function of molecular chaperones involved in collagen folding.
Isotype
IgG
Conjugate
Unconjugated
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
>95%,Protein G purified