Aliases
Proto-oncogene vav; VAV1; VAV;
Antibody Type
Polyclonal Antibody
Uniprot ID
Swiss-Prot: P15498
NCBI Gene ID: 7409
Immunogen
Synthesized non-phosphopeptide derived from human VAV1 around the phosphorylation site of tyrosine 174 (E-I-Y-E-D).
Raised In
Rabbit
Species Reactivity
Human Mouse
Tested Applications
WB IHC Recommended dilution: Western blotting: 1:500~1:3000
Background / Function
Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.Ana V. Miletic, J. Biol. Chem., Dec 2006; 281: 38257 – 38265.Christopher C. Stebbins, Mol. Cell. Biol., Sep 2003; 23: 6291 – 6299.Vered Schapira, Cancer Res., Jun 2006; 66: 6183 – 6191.Maya Groysman, J. Biol. Chem., Dec 2002; 277: 50121 – 50130.
Conjugate
Unconjugated
Storage Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
