Aliases
ATP-dependent zinc metalloprotease YME1L1, ATP-dependent metalloprotease FtsH1, Meg-4, Presenilin-associated metalloprotease, PAMP, YME1-like protein 1, YME1L1, FTSH1, YME1L, UNQ1868/PRO4304
Antibody Type
Polyclonal
Species
Human
Uniprot ID
Q96TA2
Immunogen
Recombinant human ATP-dependent zinc metalloprotease YME1L1 protein (1-240AA)
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA, IHC;Recommended dilution:IHC:1:20-1:200
Background / Function
Putative ATP-dependent protease which plays a role in mitochondrial protein metabolism. Ensures cell proliferation, maintains normal cristae morphology and complex I respiration activity, promotes antiapoptotic activity and protects mitochondria from the accumulation of oxidatively damaged membrane proteins. Requires to control the accumulation of nonassembled respiratory chain subunits (NDUFB6, OX4 and ND1). Seems to act in the processing of OPA1.
Isotype
IgG
Conjugate
Unconjugated
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Antigen Affinity Purified
Modification
ATP-dependent zinc metalloprotease YME1L1
