ACOD1 Antibody, Biotin conjugated

Aliases

Cis-aconitate decarboxylase, Aconitate decarboxylase, Aconitate decarboxylase, ACOD1

Antibody Type

Polyclonal

Species

Human

Uniprot ID

A6NK06

Immunogen

Recombinant human Cis-aconitate decarboxylase protein (57-257AA)

Raised In

Rabbit

Species Reactivity

Human

Tested Applications

ELISA;Not yet tested in other applications.

Background / Function

Involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs)-mediated inflammatory innate response by stimulating the tumor necrosis factor alpha-induced protein TNFAIP3 expression via reactive oxygen species (ROS) in LPS-tolerized macrophages. Involved in antimicrobial response of innate immune cells; ACOD1-mediated itaconic acid production contributes to the antimicrobial activity of macrophages. Plays a role in the embryo implantation.

Isotype

IgG

Conjugate

Biotin

Storage Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

>95%,Protein G purified

Modification

Cis-aconitate decarboxylase