Description
Aliases
Arg-gingipain, Gingipain 1, RGP-1, rgp1, rgpA
Antibody Type
Polyclonal Antibody
Species
Porphyromonas gingivalis
Uniprot ID
P28784
Immunogen
Recombinant Porphyromonas gingivalis Gingipain R1 protein (228-720AA)
Raised In
Rabbit
Species Reactivity
Porphyromonas gingivalis
Tested Applications
ELISA;Not yet tested in other applications.
Background / Function
Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Its proteolytic activity is a major factor in both periodontal tissue destruction and in bacterial host defense mechanisms. Activates complement C3 and C5.
Isotype
IgG
Conjugate
Biotin
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Literature
[1]”Structural characterization of argingipain, a novel arginine-specific cysteine proteinase as a major periodontal pathogenic factor from Porphyromonas gingivalis.” Okamoto K., Misumi Y., Kadowaki T., Yoneda M., Yamamoto K., Ikehara Y. Arch. Biochem. Biophys. 316:917-925(1995). [2]”Purification and characterization of a 50-kDa cysteine proteinase (gingipain) from Porphyromonas gingivalis.” Chen Z., Potempa J., Polanowski A., Wikstrom M., Travis J. J. Biol. Chem. 267:18896-18901(1992).Additional information
| Size | 50μg, 100μg |
|---|
