SGMS2 Antibody, HRP conjugated

Conjugate: HRP. Product Type: Polyclonal Antibody. Clonality: Polyclonal. Raised in: Rabbit. Isotype: IgG. Purification Method: >95%, Protein G purified. Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Form: Liquid. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Aliases: MGC26963 antibody; Phosphatidylcholine:ceramide cholinephosphotransferase 2 antibody; SGMS 2 antibody; Sgms2 antibody; SM synthase antibody; SMS 2 antibody; SMS2 antibody; SMS2_HUMAN antibody; Sphingomyelin synthase 2 antibody. Immunogen Species: Homo sapiens (Human). UniProt ID: Q8NHU3. Immunogen: Recombinant Human Phosphatidylcholine:ceramide cholinephosphotransferase 2 protein (1-79AA). Species Reactivity: Human, Rat. Tested Applications: ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:500-1:1000, IF:1:200-1:500. Background: Sphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. Plasma membrane SMS2 can also convert phosphatidylethanolamine (PE) to ceramide phosphatidylethanolamine (CPE). Major form in liver. Required for cell growth in certain cell types. Regulator of cell surface levels of ceramide, an important mediator of signal transduction and apoptosis. Regulation of sphingomyelin (SM) levels at the cell surface affects insulin sensitivity. Target: SGMS2.