Description
General description
Yohimbine hydrochloride is an α2-adrenergic receptor antagonist that blocks the central α2-adrenergic receptors in the brain and thereby prevents and decreases the effects of xylazine, an α2-adrenergic agonist. The sedation and respiratory depression that accompany xylazine administration are both antagonized and reversed by yohimbine. Yohimbine hydrochloride also produces an antidiuretic effect alongside elevated heart rate and blood pressure.
CAS No.: 131-03-3
Concentration: 90.00%
Applications and Features:
- used in vitro for its antiviral, antibacterial and antifungal activities and cytotoxic properties
- used as a tyramine receptor blocker to oppose the effects of increased tyramine in relation with flight initiation and maintenance deficits in experimental flies
- used alone and as well as with brimonidine to study the neuroprotective effect of brimonidine in the presence of glutamate-induced neurotoxicity, oxidative stress and hypoxia on in vitro cultures of purified rat retinal ganglion cells
Additional information
| Size | 1mg, 5mg, 25mg |
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