Pepsin, Mass Spec Grade

Pepsin Mass Spec (MS) Grade is the major human gastric proteases, which contributes to proteolysis of food proteins in vertebrate stomach¹.

This protease cleaves at the C-terminus of Phe, Leu, Tyr, Trp.

It can be used alone or in combination with other proteases for protein analysis by mass spectrometry and other applications.

Pepsin activity is optimal at pH 1.0–3.0. Its applications include peptide mapping, protein identification and characterization of post-translational modifications.

CAS No. 9001-75-1

Grade: Mass Spec (MS) Grade

Features/Usage:

Pepsin, Mass Spec Grade can be used-

I) for protein analysis in mass spectrometry and other applications

II) for structural protein research (HDX exchange) and antibody analysis

III) for digestion of tightly folded proteins, casein, etc.

Reference(s):

1. K.Yamamoto, et al. Cathepsin E: An Aspartic Protease with Diverse Functions and Biomedical Implications. Encyclopedia of Cell Biology. 2016. 
2. Jordan Tang. Chapter 3 – Pepsin A. Handbook of Proteolytic Enzymes. 2013